Final answer:
In acral pigmented lesions, pigment found in furrows typically signifies a benign condition known as Lentigo, which is a harmless accumulation of melanocytes. Melanoma, a serious skin cancer, usually presents with asymmetrical patches with uneven borders and a raised surface.
Step-by-step explanation:
In an acral pigmented lesion, if the pigment is observed in the furrows, it is generally considered a benign finding. The correct option that represents a benign condition with pigment in the furrows is C) Lentigo. Lentigines are benign accumulations of melanocytes on the skin and can be identified by their flat, brown appearance and are usually uniform in color. In contrast, melanoma is characterized by uncontrolled growth of melanocytes, resulting in asymmetrical, brown, and black patches with uneven borders and a raised surface, which often requires aggressive treatment including surgical excision and immunotherapy. It is the most deadly form of skin cancer and thus much more serious than benign conditions like lentigo.