Final answer:
"Low responders" to endurance exercise training may only improve their VO2 max by 5%.
Step-by-step explanation:
Genetics plays a significant role in how individuals respond to endurance exercise training. Variations in the genetic makeup, particularly the composition of slow-twitch and fast-twitch muscle fibers, contribute to differences in training outcomes. "Low responders" to endurance training may only see limited improvements in their maximal oxygen uptake or VO2 max, which is a measure of cardiovascular fitness. Studies indicate that these individuals may experience as little as a 5% increase in VO2 max with training, despite following the same regimen as those with greater genetic predisposition who may see much larger gains.