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Research reveals that long-term weight loss:

a. is independent of the macronutrient composition of the diet.
b. can be achieved by exercise alone.
c. can occur with a positive calorie diet if the extra calories come from protein.
d. Both is independent of the macronutrient composition of the diet and can be achieved by exercise alone are correct.

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Final answer:

Effective long-term weight loss typically requires a combination of a low-calorie diet and increased exercise, rather than focusing on the macronutrient composition or relying on exercise alone. Calories consumed must be fewer than those burnt to lose weight. Combining diet and exercise is the most effective strategy for weight loss.

Step-by-step explanation:

Long-Term Weight Loss Strategies

Research indicates that successful long-term weight loss is typically achieved through a combination of dietary changes and increased physical activity. A common regimen includes adhering to a low-calorie, low-fat diet and engaging in high levels of physical activity, roughly an hour of exercise per day. It is crucial to monitor food portions to ensure balance between energy consumption and expenditure. Excessive energy intake that exceeds what is burned through activity contributes to the storage of excess body fat and potential weight gain.

Regarding the macronutrient composition of the diet, while some diets may emphasize particular macronutrients, overall caloric balance is key; hence, the statement that weight loss is 'independent of the macronutrient composition of the diet' is not entirely accurate. To effectively lose weight, consuming fewer calories than burned, regardless of where these calories come from, is essential.

Weight loss efforts focusing solely on exercise alone are less likely to be effective, particularly when considering the energy content of foods compared to the energy expended during exercise. Regular exercise does increase metabolic rate but may not compensate for a high intake of calories. Protracted dieting may decrease metabolic rate, making weight loss more difficult. Considering these factors, combining diet modifications with exercise is the most effective strategy for sustaining weight loss.

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