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The term TAF is an abbreviation that stands for

a. TBP associated factor
b. translational activation factor
c. termination after finished factor
d. telomere addition factor
e. none of the above

User Katerlouis
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1 Answer

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Final answer:

TAF most likely stands for TBP-associated factor, which is involved in the assembly of transcription complexes on gene promoters during the initiation of transcription by RNA polymerase II in eukaryotes.

Step-by-step explanation:

The term TAF is most likely an abbreviation for TBP-associated factor. In the context of transcription and gene expression in eukaryotes, basal transcription factors are essential for the initiation of transcription by RNA polymerase II. These factors are designated with the prefix TFII (Transcription Factor for RNA polymerase II) followed by another letter, such as A through J, indicating a specific factor within the complex. The core component of this assembly is TFIID, of which TBP (TATA-binding protein) is a part. The TFIIA and TFIIB are then recruited and assist in the formation of the transcription initiation complex along with other factors like TFIIE, TFIIF, and TFIIH.When we discuss transcription factors, one important abbreviation that comes up frequently is TFIID, which includes the TBP and is the first to bind to the TATA box within the promoter region. The binding of TFIID to the TATA box recruits other transcription factors, allowing RNA polymerase II to bind and initiate transcription. Thus, TAF typically refers to proteins associated with TBP, playing a role in the positioning and assembly of transcription complexes on gene promoters.

User Alan Mendelevich
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