Question

In the NOD Signaling Pathway, what do Nod1 and Nod2 oligomerize and recruit?

A) MAP kinases
B) Inflammatory cytokines
C) Phospholipases
D) Caspases

Answer 1

In the NOD Signaling Pathway, Nod1 and Nod2 recruit RIP2 or RICK kinases, which activate NF-kB and MAP kinases to produce inflammatory cytokines and promote an innate immune response.

Step-by-step explanation:

In the NOD Signaling Pathway, Nod1 and Nod2 oligomerize and recruit a set of serine-threonine kinases known as RIP2 or RICK. These kinases then initiate downstream signaling events leading to the activation of important transcription factors such as NF-κB and MAP kinases. This activation results in the production of inflammatory cytokines, chemokines, and other effector molecules that are essential for the innate immune response to bacterial invasion.