Final answer:
The Anti-mitochondrial antibody (AMA) is associated with primary biliary cholangitis/cirrhosis, an autoimmune disease affecting the liver's small bile ducts.
Step-by-step explanation:
The antibody associated with primary biliary cholangitis/cirrhosis is the Anti-mitochondrial antibody (AMA). Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is an autoimmune disease of the small bile ducts. In this condition, the body's immune system attacks the small bile ducts of the liver, leading to damage and subsequently cirrhosis if left untreated. AMA is the most commonly associated antibody and is often used as a diagnostic marker for the disease. By contrast, Anti-smooth muscle antibody (ASMA) is more associated with autoimmune hepatitis, Anti-double stranded DNA (Anti-dsDNA) is specific for systemic lupus erythematosus (SLE), and Anti-SSA/Ro antibody is associated with Sjogren's syndrome and also SLE.