129k views
0 votes
Patient with flaccid bullae and mucosal erosions Bx showing intraepidermal cleavage and immunofluorescence showing intercellular IgG in the epidermis:

a) Bullous pemphigoid; Corticosteroids
b) Pemphigus vulgaris; Corticosteroids + immunosuppressants
c) Dermatitis herpetiformis; Dapsone + gluten-free diet
d) Epidermolysis bullosa acquisita; Corticosteroids + immunosuppressants

User Jieren
by
8.4k points

1 Answer

4 votes

Final answer:

A patient with flaccid bullae, mucosal erosions, intraepidermal cleavage on biopsy, and intercellular IgG deposits in the epidermis likely has Pemphigus vulgaris, which is treated with corticosteroids and immunosuppressants.

Step-by-step explanation:

A patient presenting with flaccid bullae and mucosal erosions with biopsy intraepidermal cleavage and direct immunofluorescence showing intercellular IgG deposits in the epidermis is indicative of Pemphigus vulgaris. This is an autoimmune disorder characterized by the body's immune system attacking the connections between epidermal cells, leading to blistering of the skin and mucous membranes. The treatment for Pemphigus vulgaris is a combination of corticosteroids and immunosuppressants to reduce inflammation and modulate the immune response.

User Jmtoung
by
7.9k points