Question

Patient post-bone marrow transplant develops maculopapular rash, blood-positive diarrhea, and abnormal LFTs and jaundice:

a) CMV infection
b) Graft-versus-host disease (GVHD)
c) Adenovirus infection
d) Aspergillus infection

Answer 1

GVHD is the disease associated with bone marrow transplants and occurs when the immune cells in the transplanted tissue attack the recipient's cells. Symptoms include rash, diarrhea, abnormal LFTs, and jaundice.

Step-by-step explanation:

Graft-versus-host disease (GVHD) is the disease associated with bone marrow transplants. GVHD occurs when the immune cells in the transplanted tissue recognize the recipient's cells as foreign and attack them. The symptoms of GVHD can include a maculopapular rash, blood-positive diarrhea, and abnormal liver function tests (LFTs) and jaundice. GVHD can occur in both acute and chronic forms and can affect various organs.