Final answer:
Peptide hormones are water-soluble and lipophobic with short half-lives, requiring membrane-bound receptors for action, while steroid hormones are lipid-soluble, have longer half-lives, and can directly enter cells to interact with intracellular receptors.
Step-by-step explanation:
The classification of hormones can be a complex topic, taking into account their solubility, structure, and mechanism of action in the body. Peptide hormones are water-soluble and lipophobic, meaning they can't diffuse through the lipid bilayer of cell membranes and must utilize membrane-bound receptors and signal transduction systems to exert their effects. They tend to have short half-lives, often measured in minutes, due to their rapid breakdown and excretion. In contrast, steroid hormones are lipid-soluble (lipophilic) and can cross cell membranes directly to interact with intracellular receptors.
Derived from cholesterol, these hormones usually exhibit longer half-lives and often travel in the bloodstream bound to protein carriers. The lag time before observable effects can be seen is often associated with steroid hormones due to the time needed for gene transcription and subsequent protein synthesis, which can take around 90 minutes or more.