Final answer:
A blowing holosystolic murmur at LLSB increasing with inspiration is most commonly associated with mitral regurgitation (d).
Step-by-step explanation:
A blowing holosystolic murmur at LLSB (left lower sternal border) increasing with inspiration is most commonly associated with mitral regurgitation (d).
Mitral regurgitation is the backflow of blood from the left ventricle to the left atrium due to a dysfunctional mitral valve. The blowing quality of the murmur, along with its timing during systole and its location at the left lower sternal border, helps differentiate it from other heart conditions.