Final answer:
For penicillin-allergic patients, doxycycline and ceftriaxone are suitable alternative treatments for syphilis. Azithromycin may be used but is less effective and requires follow-up testing. Clindamycin is not commonly used for this purpose.
Step-by-step explanation:
The recommended treatment for syphilis in patients who are allergic to penicillin includes alternatives such as doxycycline and ceftriaxone. Doxycycline is a tetracycline antibiotic that is effective for treating various infections, including syphilis, when penicillin cannot be used. Ceftriaxone, a beta-lactam antibiotic, can also be administered, usually intravenously, for the treatment of syphilis in penicillin-allergic patients.
Azithromycin is another antibiotic that may be considered; however, it tends to be less effective for syphilis and requires retesting post-treatment to ensure cure. Clindamycin is not typically recommended for treating syphilis. Therefore, the most appropriate alternate treatments for syphilis in a penicillin-allergic individual would be doxycycline or ceftriaxone.