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From the (basal) surface to the (apical) surface of an epithelial cell, what is the order of cell junctions observed in the junctional complex?

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Final answer:

The order of cell junctions from basal to apical surfaces in epithelial cells is tight junctions, adherens junctions, desmosomes, and hemidesomes.

Step-by-step explanation:

From the basal surface to the apical surface of an epithelial cell, the order of cell junctions observed in the junctional complex is typically as follows:

  1. Tight junctions: These are at the apical region of the cell and create a barrier that restricts the flow of substances between the cells.
  2. Adherens junctions: Positioned just below the tight junctions, they encircle the cell and provide strong mechanical attachments between adjacent cells through cadherin proteins and actin filaments.
  3. Desmosomes: Located below adherens junctions, these patch-like structures provide strong adhesion by linking to intermediate filaments inside the cell.
  4. Hemidesmosomes: Found at the basal surface, these half-desmosome structures attach epithelial cells to the basal lamina via integrins.

This order of junctions enables epithelial tissues to function as selective barriers and maintain structural integrity while being flexible.

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