Final answer:
In skin pathology, a fissure can potentially lead to ulceration, which is a deeper loss of skin layers and the formation of ulcers.
Step-by-step explanation:
The question asks what a fissure often leads to. A fissure, when referred to in the context of skin pathology, is a groove or crack-like sore that commonly affects the skin. A fissure itself is not listed as an option among the choices provided. However, considering the context of the skin conditions mentioned in the choices, a fissure can potentially lead to an ulceration, which is a deeper loss of skin layers that may result in the formation of ulcers.