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Many autoinflammatory diseases associated with the inflammasome are caused by excessive basal production of _____. We treat these with what?

A) Interleukin-1, IL-1 receptor antagonist
B) Interferon-gamma, corticosteroids
C) Tumor necrosis factor, anti-TNF drugs
D) Interleukin-6, monoclonal antibodies

1 Answer

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Final answer:

Autoinflammatory diseases associated with the inflammasome are caused by excessive basal production of interleukin-1. These diseases can be treated with IL-1 receptor antagonist.

Step-by-step explanation:

Many autoinflammatory diseases associated with the inflammasome are caused by excessive basal production of interleukin-1. These diseases can be treated with IL-1 receptor antagonist, which inhibits the activity of interleukin-1 and reduces inflammation. Many autoinflammatory diseases associated with the inflammasome are caused by excessive basal production of Interleukin-1 (IL-1). The treatment for these conditions is typically the use of an IL-1 receptor antagonist. In this response, A) Interleukin-1, IL-1 receptor antagonist is the correct answer. Interleukin-1 is a pro-inflammatory cytokine that plays a critical role in the body's immune response by driving inflammation. When its production is excessive, it can lead to autoinflammatory disorders. IL-1 receptor antagonists work by blocking the action of IL-1, thereby reducing inflammation and its associated symptoms. This is in contrast to other treatments such as corticosteroids which are more broadly acting immunosuppressive and anti-inflammatory drugs, or monoclonal antibodies and anti-TNF drugs that target other specific components of the immune system.