Final answer:
Subsequent HSV outbreaks reoccur at the site of the initial lesion, which is the first sign of infection that HSV presents after entering the body.
Step-by-step explanation:
In the context of Herpes Simplex Virus (HSV) infections, subsequent outbreaks will always reoccur at the site of the initial lesion. The initial lesion refers to the first visible sign of the infection on the skin or mucous membranes. In HSV, this could be the first cold sore or genital lesion that appears after viral entry. Once HSV enters the body, it establishes latency in the local sensory ganglia and can reactivate to cause recurrent lesions in the same site as the initial lesion due to this localized latency.