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Human antibody-mediated diseases (type II hypersensitivity): Goodpasture syndrome

A) Glomerulonephritis
B) Destruction of platelets
C) Inflammation of joints
D) Damage to the thyroid gland

User OrangeInk
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Final answer:

Type II hypersensitivity reactions involve the binding of antibodies to cell-surface antigens, leading to cell damage. Goodpasture syndrome is a type II hypersensitivity disease that affects the kidneys and lungs.

Step-by-step explanation:

Type II hypersensitivity reactions involve the binding of IgG and IgM antibodies to cell-surface or matrix-associated antigens, leading to cell damage mediated by complement activation or antibody-dependent cell-mediated cytotoxicity (ADCC). Examples of type II hypersensitivity include mismatched blood transfusions and blood compatibility diseases. Goodpasture syndrome is a type II hypersensitivity disease characterized by autoantibodies targeting the basement membrane in the kidneys and lungs, leading to glomerulonephritis and lung damage.

User Lezz
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