Question

The BRCA1 and BRCA2 genes are master genes that regulate other genes in the cell-such as the genes responsible for cell growth and replication and DNA repair. If these genes are damaged or altered through mutation

then it might affect the cell's control over the processes of cell growth and replication or the ability to repair DNA.
Imagine a study looking at the effect of BRCA1 and BRCA2 on breast cancer in women. The researchers found subjects who did not have breast cancer and identified whether they had a mutation in SRCAT, a mutation in
BRCA2, or no mutation in either of the BRCA genes. (This study did not include people who had mutations in both BRCA1 and BRCA2) The researchers identified the genes of each subject and then collected data from all the
subjects during a 30-year period to determine how many eventually developed breast cancer. The following table presents the results of this hypothetical study. Use the data to determine the percentage of subjects in
each group who developed breast cancer. Type that percentage number into the table where indicated.
Please round your percentage answer to the nearest whole number.
Number of subjects followed
Number of subjects who developed breast cancer
Percentage of subjects who developed breast cancer
BRCA1 Mutation
980
568
enter answer
BRCA2 Mutation
1020
612
enter answer
No BRCA Mutation
1040
125
enter answer
By analyzing the results of this study, you can conclude that for a woman who does not have a mutated BRCA gene. the normal risk of getting breast cancer is
enter answer

Answer 1

The percentage of subjects who developed breast cancer in each group are 58% for BRCA1 Mutation, 60% for BRCA2 Mutation, and 12% for No BRCA Mutation.

Step-by-step explanation:

The percentage of subjects who developed breast cancer in each group can be calculated by dividing the number of subjects who developed breast cancer by the total number of subjects in each group, and then multiplying by 100. Using the data provided, we can calculate the percentages as follows:

BRCA1 Mutation: 568 / 980 × 100 = 58%

BRCA2 Mutation: 612 / 1020 × 100 = 60%

No BRCA Mutation: 125 / 1040 × 100 = 12%

Based on the results of this study, we can conclude that for a woman who does not have a mutated BRCA gene, the normal risk of getting breast cancer is approximately 12%.