Final answer:
The antibiotic no longer being effective indicates that the bacteria has developed resistance through natural selection.
Step-by-step explanation:
The fact that the antibiotic initially worked but is no longer effective indicates that the streptococcus bacterium has experienced natural selection, allowing the resistant streptococcus to survive and multiply. Antibiotic resistance occurs when bacteria change in a way that reduces the effectiveness of drugs designed to kill them. The resistant bacteria survive and continue to multiply, causing more harm. This is a result of overuse and incorrect use of antibiotics, which leads to the natural selection of resistant forms of bacteria.