Final answer:
To calculate the yield of cyclohexanone reduction with NaBH4, weigh the reactants and product, use molecular weights to determine theoretical yield, and compare actual weight of purified product to calculate percent yield.
Step-by-step explanation:
Calculating Yield for Cyclohexanone Reduction with NaBH4
To calculate the yield of cyclohexanone reduction with NaBH4, you would first need to determine the stoichiometry of the reaction. Assuming a complete conversion where each mole of cyclohexanone reacts with one mole of NaBH4, you would weigh the amount of cyclohexanone you start with and record the molecular weight of both cyclohexanone and the product cyclohexanol. Post-reaction, you would purify and weigh your product, cyclohexanol. The theoretical yield is obtained by using the molecular weights and initial amount of cyclohexanone, and the actual yield is the purified weight of cyclohexanol you obtained from the experiment. The percent yield is then calculated using the ratio of the actual yield to the theoretical yield multiplied by 100.
Since your NMR analysis shows a product mixture, the percent yield would be calculated based on the amount of desired product relative to the total mixed products. A 2:1 ratio of the desired product to a byproduct would require you to consider the proportion of the NMR integral areas corresponding to the desired product peaks versus the total area for all products.