Final answer:
Most historical expansion during the 1400s to 1600s occurred within A-f-ro-Eurasia, involving Africa, Europe, and Asia, driven by European exploration and colonization as well as cultural developments like the Renaissance.
Africa and Europe , is the correct answer.
Step-by-step explanation:
The period of expansion outlined in your question coincides with the time when trade and colonization efforts were ramping up in the early modern era, particularly between the 1400s and 1600s. During this time, the regions that saw the most significant expansion were largely focused on A-f-ro-Eurasia, which covers Africa, Europe, and Asia. Major European powers like Portugal, Spain, England, and France engaged in the Age of Discovery, initiating the European exploration and colonization that led to the establishment of trade routes with Asia and the colonization of coastal Africa. This expansion created a dynamic world where Africa, Europe, and parts of Asia were increasingly interconnected economically and politically.
In parallel, the Renaissance began in Italy, spreading throughout Europe and heralding a surge in cultural accomplishments and an emphasis on trade.
In summation, most historical expansion during the specified period occurred within A-fr-o-Eurasia, with significant movements between Europe, Africa, and Asia, but not so much involving South America at the time.