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What is the therapeutic level monitoring requirement for Aminophylline (airway spasms), Dilantin (anticonvulsant), and Bilirubin?

A) Aminophylline: Blood glucose levels
B) Dilantin: Serum potassium levels
C) Bilirubin: Serum bilirubin levels
D) Aminophylline: Serum theophylline levels, Dilantin: Serum phenytoin levels, Bilirubin: Serum bilirubin levels

1 Answer

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Final answer:

The therapeutic level monitoring requirements are Aminophylline: Serum theophylline levels, Dilantin: Serum phenytoin levels, and Bilirubin: Serum bilirubin levels, corresponding to answer choice (D). Therapeutic drug monitoring ensures drug efficacy and safety by maintaining appropriate serum drug levels.

Step-by-step explanation:

The therapeutic level monitoring requirements for Aminophylline (used to treat airway spasms), Dilantin (an anticonvulsant), and Bilirubin are as follows:

  • Aminophylline: Serum theophylline levels
  • Dilantin: Serum phenytoin levels
  • Bilirubin: Serum bilirubin levels

Thus, the correct answer to the question is (D) Aminophylline: Serum theophylline levels, Dilantin: Serum phenytoin levels, and Bilirubin: Serum bilirubin levels. The purpose of therapeutic drug monitoring (TDM) is to individualize drug dosing by maintaining plasma or serum drug levels within a target range. The target range should be narrow enough to ensure efficacy without causing toxicity. This practice is especially important for medications with a narrow therapeutic range, like Aminophylline and Dilantin, where incorrect dosing could lead to significant side effects or decreased effectiveness.

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