Final answer:
The insured and the insurance agent are required to sign the Notice Regarding Replacement of Medicare Supplement Coverage. This document is not signed by the primary care physician or the state insurance commissioner.
Step-by-step explanation:
The individual required to sign the Notice Regarding Replacement of Medicare Supplement Coverage is typically the insured and the insurance agent. The Notice is part of the consumer protection aspect of the insurance sales process, ensuring that policyholders are fully informed about the implications of replacing their current Medicare supplement coverage. The primary care physician and the state insurance commissioner do not sign this document, as it is specifically related to the insurance contract between the insured and the insurance company, facilitated by the agent.