Final answer:
The question covers genetic linkage and recombination frequency, highlighting the concepts of constructing linkage maps based on how frequently genes cross over during meiosis, thereby informing their relative distances on a chromosome.
Step-by-step explanation:
The question pertains to genetic linkage and recombination frequency, which are key concepts in understanding how genes are inherited and mapped on chromosomes. When genes such as Gene M and Gene B are situated in a hot spot for crossing over, they are more likely to undergo recombination during meiosis compared to genes that are not in a hot spot, like Gene D and Gene L, despite being the same physical distance apart. The linkage map is constructed by using frequencies of crossing-over to establish the relative distances between genes on a chromosome. Genes that are further apart have a higher likelihood of crossing over, which means they will assort independently more frequently, as explained in the provided reference. Therefore, the recombination frequency not only provides the order of the genes but also an estimate of their physical distance from each other.