Final answer:
Glanzmann Thrombasthenia is a rare genetic disorder caused by mutations in the ITGA2B or ITGB3 genes, leading to deficient or malfunctioning glycoprotein IIb/IIIa complex necessary for platelet aggregation in the blood clotting process.
Step-by-step explanation:
Glanzmann Thrombasthenia is a rare genetic disorder that is characterized by a condition where the blood doesn't clot as it should. The cause of Glanzmann Thrombasthenia is a mutation in the genes ITGA2B or ITGB3. These genes are responsible for producing the glycoprotein IIb/IIIa complex, which is essential for platelet aggregation, a critical step in the blood clotting process. A mutation in either of these genes can result in a deficiency or malfunction of this platelet membrane receptor, leading to the symptoms associated with the disorder. Affected individuals tend to experience prolonged bleeding times, even with minor injuries, because their platelets cannot form proper blood clots.