Final answer:
The nurse's priority intervention is to maintain a PaCO2 level of approximately 35 mm Hg.
Step-by-step explanation:
The nurse's priority intervention for a client with a closed head injury and receiving mechanical ventilation is to maintain a PaCO2 of approximately 35 mm Hg.
PaCO2 refers to the partial pressure of carbon dioxide in the arterial blood. In a closed head injury, elevated PaCO2 can lead to increased intracranial pressure, which can worsen the patient's condition.
Other interventions mentioned in the options are important, but maintaining a proper PaCO2 level is the priority.