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What is Proximal Convoluted Tubule (PCT)

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Final answer:

The Proximal Convoluted Tubule (PCT) is the first part of the renal tubule that processes the filtrate from Bowman's capsule. It reabsorbs water, ions, and nutrients, and is vital for pH balance and toxin removal. It is structurally adapted for these roles with microvilli and abundant mitochondria.

Step-by-step explanation:

The Proximal Convoluted Tubule (PCT) plays a pivotal role in the renal system's task of filtering blood and forming urine. Forming part of the nephron, it is the first site where the filtrate from Bowman's capsule is extensively modified. This section is named for its twisted or convoluted shape, allowing a greater surface area for the absorption and secretion processes. It comprises cells with simple cuboidal epithelium, highly characteristic due to the conspicuous brush border of microvilli on their luminal surface. This arrangement is critical for maximizing the reabsorption of solutes such as sodium (Na+), chloride (Cl-), and glucose. Furthermore, the PCT cells are metabolically active, necessitating a significant abundance of mitochondria to supply the energy (in the form of ATP) required for active transport mechanisms key to renal function.

Within the PCT, there is also the task of pH regulation, toxin removal, and reabsorption of water and nutrients, thus ensuring the body retains essential components while excreting waste products. The function of the PCT can be contrasted with that of the Distal Convoluted Tubule (DCT), which also contributes to the active transport of ions but has a reduced role in absorption evidenced by fewer microvilli.

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