Final answer:
The second GTP hydrolysis in initiation initiates translation.
Step-by-step explanation:
The second GTP hydrolysis in initiation initiates translation. In translation, the complex that assembles to start the process is referred to as the initiation complex. The first protein to bind to the RNA and initiate translation is the eukaryotic initiation factor-2 (eIF-2), which is active when it binds to the high-energy molecule guanosine triphosphate (GTP). After the initiation complex is assembled, the GTP is converted into guanosine diphosphate (GDP) and energy is released, allowing the large ribosomal subunit to bind and initiate translation.