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What causes a graded potential to degrade?

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Final answer:

Graded potentials can degrade due to the movement of ions. Depolarizing graded potentials are the result of positive ions entering the cell, while hyperpolarizing graded potentials are caused by negative ions entering or positive ions leaving the cell.

Step-by-step explanation:

Graded potentials can be of two sorts, either they are depolarizing or hyperpolarizing. Depolarizing graded potentials are often the result of Na+ or Ca²+ ions entering the cell, which causes the cell to become less negative. Hyperpolarizing graded potentials can be caused by K+ leaving the cell or Cl- entering the cell, which makes the cell more negative. Both depolarizing and hyperpolarizing graded potentials can degrade due to the movement of ions.

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