Final answer:
Drugs affecting microtubules in cancer have multiple effects on cancer cells, including inducing apoptosis, inhibiting DNA synthesis, and blocking cell cycle progression.
Step-by-step explanation:
The use of drugs affecting microtubules in cancer is justified because these drugs can have several effects on cancer cells. One rationale is that they induce apoptosis, which is programmed cell death. By interfering with microtubule assembly and disassembly, these drugs can disrupt mitosis and prevent cells from dividing, ultimately leading to cell death. Additionally, by inhibiting DNA synthesis and blocking cell cycle progression, these drugs can further inhibit cancer cell growth.