Final answer:
Cell cycle progression would be a good anti-cancer drug target as it can help control and inhibit the growth of cancer cells.
Step-by-step explanation:
The best anti-cancer drug target among the options provided would be cell cycle progression. Cancer cells often have uncontrolled cell division and can bypass normal checkpoints in the cell cycle. Targeting the proteins and pathways involved in cell cycle progression can help control and inhibit the growth of cancer cells.