Question

C3b is a ligand (substrate) for Macrophage CR1.
a) True
b) False

Answer 1

C3b is not a ligand for Macrophage CR1.

Step-by-step explanation:

False

C3b is not a ligand (substrate) for Macrophage CR1. The larger fragment, C3b, binds to the surface of the pathogen and activates the rest of the complement cascade. Phagocytic cells such as macrophages and neutrophils are attracted to the site of infection by chemotactic attraction to smaller complement fragments, but C3b itself is not a ligand for Macrophage CR1.