Question

What do intermediate neural tube explants express in the absence of Shh?

a) BMP inhibitors
b) FGF signaling molecules
c) Sonic hedgehog (Shh)
d) Wnt ligands

Answer 1

During organogenesis, the ectoderm forms epithelial cells and neuronal tissues. Growth factors signal some cells at the edge of the ectoderm to become epidermis cells, while the remaining cells in the center form the neural plate.

Step-by-step explanation:

In vertebrates, one of the primary steps during organogenesis is the formation of the neural system. The ectoderm forms epithelial cells and tissues, and neuronal tissues. During the formation of the neural system, special signaling molecules called growth factors signal some cells at the edge of the ectoderm to become epidermis cells. The remaining cells in the center form the neural plate. If the signaling by growth factors were disrupted, then the entire ectoderm would differentiate into neural tissue.