Question

CD34 and GlyCAM1 are examples of what?

a) Chemokines
b) Cytokines
c) Vascular addressins
d) Immunoglobulins

Answer 1

CD34 and GlyCAM1 are examples of vascular addressins, which are molecules that facilitate the attachment of leukocytes to the endothelium during an immune response. Thus, option c) Vascular addressins is the correct answer.

Step-by-step explanation:

CD34 and GlyCAM1 are examples of vascular addressins. Vascular addressins are a type of molecule found on endothelial cells that line blood vessels. They play a critical role in the immune system by guiding the movement of lymphocytes to specific tissues.

During an immune response, addressins, such as CD34 and GlyCAM1, interact with selectins on leukocytes (white blood cells) to facilitate the leukocytes' attachment to the vascular endothelium, a process known as lymphocyte homing.

This attachment is necessary before the leukocytes can extravasate (move out of the blood vessel) and enter the surrounding tissue where they may be needed for an immune response.

Therefore, the correct answer to the given question is option c) Vascular addressins.

Answer 2

CD34 and GlyCAM1 are examples of vascular addressins. These glycoproteins play a crucial role in immune response and leukocyte migration. CD34 is also a marker for hematopoietic stem cells.

Therefore, the correct answer to the given question is option c) Vascular addressins.

Step-by-step explanation:

CD34 and GlyCAM1 are examples of vascular addressins, which are a type of glycoproteins that mediate the adhesion of leukocytes to the vascular endothelium, enabling their movement from the bloodstream to tissues.

These molecules are crucial for the proper functioning of the immune system, especially during early induced responses, and later during adaptive immune responses.

CD34 is also a well-known marker used to identify hematopoietic stem cells in bone marrow transplantation procedures, while GlyCAM1 is an addressin that directs the migration of leukocytes to lymph nodes.

Therefore, the correct answer to the given question is option c) Vascular addressins.