Final answer:
Follow-up care for Rh incompatibility, involving the administration of RhoGAM, should occur as needed, specifically during the 26th to 28th weeks of pregnancy and within 72 hours after delivery. It has significantly reduced the incidence of HDN.
Step-by-step explanation:
Follow-up care for Rh incompatibility should occur as needed, with a specific schedule for the administration of RhoGAM. RhoGAM, also known as Rh immune globulin, is generally administered to the Rh-negative pregnant individual during weeks 26-28 of pregnancy and within 72 hours following birth. It may also be given after events potentially causing transplacental hemorrhage such as amniocentesis or abdominal trauma. RhoGAM's introduction significantly reduced the incidence of hemolytic disease of the newborn (HDN) from about 13-14 percent to approximately 0.1 percent in areas like the United States.