Final answer:
During the workup of endometrial cancer, the primary labs obtained should be an endometrial biopsy and a transvaginal ultrasound. These tests provide essential information on the presence of cancer cells in the uterus and the structure of gynecological organs. Other tests like CA-125 or Pap smear are not definitive for endometrial cancer diagnosis.
Step-by-step explanation:
The workup of endometrial cancer typically includes labs that allow for the evaluation of the uterine environment and the extent of potential cancer spread. The most definitive tests for this purpose are endometrial biopsy and transvaginal ultrasound. Endometrial biopsy is a procedure where a sample of the tissue lining the uterus is removed and examined under a microscope for cancerous cells. A transvaginal ultrasound uses sound waves to create images of the uterus, which can help identify abnormalities in the uterine lining and other gynecological organs.
While CA-125 levels can be elevated in endometrial cancer, this test alone is not sufficient for diagnosis. Likewise, Pap smear and HPV testing are primarily used to screen and diagnose cervical cancer, not endometrial cancer. Progesterone and hCG levels are not routinely assessed in the workup of endometrial cancer. Therefore, the answer to the question 'What labs should be obtained during the workup of endometrial cancer?' is d) Endometrial biopsy and transvaginal ultrasound.