Final answer:
The 'Multi-hit model' of cancer suggests that cancer develops through a series of genetic alterations, starting with an initiating event followed by promoting factors and progression to a more malignant state.
Step-by-step explanation:
The 'Multi-hit model' of cancer proposes that cancer develops through a series of cumulative genetic alterations, starting with an initiating event, followed by promoting factors and progression to a more malignant state. It emphasizes the complexity and heterogeneity of cancer, highlighting the need for comprehensive understanding for effective treatment strategies.