Question

When p53 does not act like a police officer, what does it mean?

A) Enhanced tumor suppression
B) Arrest of cell cycle
C) Loss of tumor suppression
D) Increased apoptosis

Answer 1

When p53 is not functioning as it should, there is a loss of tumor suppression. This leads to cell cycle progression without proper DNA repair or apoptosis, resulting in tumor growth. option c is answer

Step-by-step explanation:

When p53 does not act like a police officer, it means there is a loss of tumor suppression. Normally, p53 helps to monitor the cell cycle and ensure that cells with damaged DNA either repair the damage or undergo apoptosis (programmed cell death).

If p53 is not functioning correctly, it cannot stop the cell cycle to repair DNA nor can it initiate apoptosis. This leads to the proliferation of cells with mutations, and eventually, tumor growth. In this context, malfunctioning p53 is similar to having faulty brakes in a car, where both can lead to disastrous consequences. option c is answer