Question

How does fluid enter the Bowman's capsule lumen from the lumen of the glomerular capillaries?

a. Fluid gets pushed between the cells (no tight junctions).
b. Active transport through specialized channels.
c. Diffusion through tight junctions.
d. Facilitated diffusion across the capillary walls.

Answer 1

Fluid enters the Bowman's capsule through hydrostatic pressure, which is the primary driving force pushing water and solutes from the glomerular capillaries into the capsule.

Step-by-step explanation:

Fluid enters the Bowman's capsule lumen from the lumen of the glomerular capillaries primarily through a process known as hydrostatic pressure. This pressure is generated by the blood as it enters the high-pressure environment of the glomerulus, which facilitates the filtration of water and solutes out of the blood into Bowman's capsule. The high osmotic pressure from the retained solutes within the blood vessel creates a gradient that does not permit large molecules like proteins to pass, maintaining the force necessary for filtration.