Question

FH patients have mutations in -----------.
a. LDL cholesterol particles
b. LDL receptors

Answer 1

FH patients have mutations in LDL receptors.

Step-by-step explanation:

FH patients have mutations in

1. LDL cholesterol particles
2. LDL receptors

Patients with familial hypercholesterolemia (FH) have mutations either in the LDL receptor gene or the ApoB gene, resulting in defective or missing LDL receptors. This condition leads to life-threatening levels of cholesterol in the blood since LDL particles cannot be cleared from the blood effectively.