Final answer:
The opening of voltage-gated Na+ channels during the rising phase of an action potential occurs when the membrane potential reaches the threshold potential.
Step-by-step explanation:
The condition that triggers the opening of voltage-gated Na+ channels during the rising phase of an action potential is b) Threshold potential reached by the membrane voltage. When the membrane potential reaches a certain threshold, typically around -55 millivolts, these channels open and allow an influx of Na+ ions into the neuron. This causes further depolarization, leading to the rising phase of the action potential where the membrane potential swiftly changes from negative to positive.