Final answer:
The engineering of insulin lispro is an example of site-directed mutagenesis, which allows for the creation of synthetic insulin beneficial for people with diabetes.
Step-by-step explanation:
The engineering of insulin lispro, a synthetic insulin with reversed lysine and proline residues at the C-terminal end of the B-chain for rapid absorption, is an example of site-directed mutagenesis. This is a method in molecular biology and genetic engineering where specific changes are introduced to a predetermined sequence in a DNA molecule. Through recombinant DNA technology, bacteria can be engineered to produce human insulin by introducing the human insulin gene into the bacterial DNA, allowing the bacteria to act as tiny factories synthesizing the protein. Human insulin produced in this way was the first human protein to be manufactured through such technology, significantly benefitting individuals with diabetes who require external sources of insulin.