Final answer:
The mitochondria are the organelles responsible for generating energy from glucose in cells.
Step-by-step explanation:
The organelle responsible for generating energy from the oxidation of glucose to carbon dioxide and water in cells is the mitochondria. In a patient with diabetes, who presents with ketoacidosis, there is an initial lack of insulin that would normally facilitate the uptake of glucose into the cells. After treatment, once glucose is able to enter the cells, it is the mitochondria that play a crucial role in cellular respiration, converting glucose into adenosine triphosphate (ATP) which cells use as an energy source.