Final answer:
To access the ampule, the nurse should first wipe the constricted neck with an alcohol swab. Then, the nurse can insert the needle into the center of the rubber seal.
Step-by-step explanation:
To access the ampule, the nurse should wipe the constricted neck with an alcohol swab first. This is done to ensure that the area is clean and free from any contaminants. After wiping, the nurse can then proceed to insert the needle into the center of the rubber seal in order to access the medication inside the ampule.