Final answer:
The nurse should instill the solvent according to the manufacturer's instructions to reconstitute powdered medication, maintaining aseptic technique throughout the process.
Step-by-step explanation:
When a nurse must reconstitute a powdered medication, it is vital to follow the manufacturer's instructions and maintain aseptic technique. The correct answer is to instill the solvent as per the manufacturer's directions. This typically involves several steps: weighing the appropriate mass of the powdered medication, adding it to a volumetric flask partially filled with distilled water, swirling the solution to dissolve the solute, further filling the flask to the etched line with distilled water, capping and inverting the flask multiple times to ensure complete mixing, and applying aseptic techniques to avoid contamination during the transfer process.