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Explain the pathological conditions associated with Addison's Disease, particularly its impact on the adrenal cortex. Provide a brief overview.

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Final answer:

Addison's disease is a disorder characterized by hyposecretion of the adrenal cortex hormone cortisol. It can be caused by autoimmune responses, pituitary gland dysfunction, or infections. Treatment involves replacement hormone therapy.

Step-by-step explanation:

Addison's disease is a disorder characterized by hyposecretion of the adrenal cortex hormone cortisol. It can be caused by autoimmune responses, pituitary gland dysfunction, or infections. The immune system produces abnormal antibodies that attack the adrenal cortex, leading to decreased cortisol production. Symptoms of Addison's disease include hyperpigmentation of the skin, excessive fatigue, low blood pressure, and salt cravings. Treatment involves replacement hormone therapy.

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