Question

What are the three primary steps involved in targeting vesicles to specific compartments within the cell?

A) 1. Vesicle formation, 2. Budding from Golgi, 3. Fusion with lysosomes
B) 1. Cargo selection, 2. Vesicle budding, 3. Specific receptor recognition
C) 1. Endocytosis, 2. Transcription, 3. Exocytosis
D) 1. Protein translation, 2. Sorting in the cytoplasm, 3. Nuclear import

Answer 1

The three primary steps involved in targeting vesicles to specific compartments within the cell are cargo selection, vesicle budding, and specific receptor recognition.

Step-by-step explanation:

The three primary steps involved in targeting vesicles to specific compartments within the cell are:

1. Cargo selection: Cargo receptor proteins in the membranes of the trans Golgi stack bind to specific packaged proteins (cargo proteins).
2. Vesicle budding: Cargo protein-bound receptor proteins bud off from the trans Golgi stack with the help of clathrin and other COP proteins.
3. Specific receptor recognition: The budding vesicles acquire V-SNARE (vesicle-SNARE) proteins which bind to complementary T-SNARE (target-SNARE) proteins on the receiving membranes, resulting in fusion of the vesicle with its target compartment.