Question

Types of SNAREs involved in docking vesicles to target compartment target vesicles to particular compartment

A) T-SNAREs (Target SNAREs)
B) R-SNAREs (Receptor SNAREs)
C) V-SNAREs (Vesicle SNAREs)
D) C-SNAREs (Compartment SNAREs)

Answer 1

SNAREs are proteins that facilitate the fusion of vesicles with target compartments. V-SNARE proteins on vesicles bind to T-SNARE proteins on target membranes, enabling the delivery of vesicle contents to specific cellular locations, such as during receptor-mediated endocytosis.

Step-by-step explanation:

The types of SNAREs involved in docking vesicles to their target compartments are crucial for cellular transport processes. V-SNAREs (vesicle-SNAREs) are present on the membrane of transport vesicles, whereas T-SNAREs (target-SNAREs) are located on the membranes of the target compartments. During the process of vesicle fusion, V-SNAREs on the vesicles bind to complementary T-SNAREs on the receiving membranes, leading to membrane fusion and delivery of the vesicle contents.

For example, at the trans face of the Golgi apparatus, cargo proteins are packaged into vesicles that contain specific V-SNARE proteins on their membranes. These vesicles then fuse with appropriate target membranes that have the matching T-SNAREs, ensuring that the cargo proteins reach their correct cellular destination. Similarly, in receptor-mediated endocytosis, extracellular substances are taken up through vesicles that are then targeted to specific compartments within the cell for processing.