Final answer:
Pelvic inflammatory disease (PID) is a significant cause of infertility, often resulting from sexually transmitted infections that lead to scarring and blockage of the fallopian tubes.
Step-by-step explanation:
Pelvic inflammatory disease (PID) is indeed a major cause of infertility. PID is an infection of the female reproductive organs. It most commonly stems from sexually transmitted infections, such as Neisseria gonorrhoeae and Chlamydia trachomatis. One serious form of PID is salpingitis, an inflammation of the fallopian tubes, which can cause scarring and blockage, preventing sperm from reaching an egg for fertilization. This scarring and blockage can lead to infertility as well as increase the risk of ectopic pregnancy, a dangerous condition where the fertilized egg implants outside the uterus.
PID can have various symptoms, including but not limited to lower abdominal pain, vaginal discharge, fever, and painful urination. If left untreated, PID can result in long-term health issues such as chronic pelvic pain and significant difficulties with fertility. Thus, the assertion that Pelvic inflammatory disease is a major cause of infertility is true.