Question

A patient with chronic kidney failure is taking a loop diuretic. The nurse will advise the patient to take the drug

1. with food.
2. in the morning.
3. at bedtime.
4. in the late afternoon.

Answer 1

Patients should take loop diuretics in the morning to avoid sleep disruptions due to increased urination, as these drugs inhibit the reabsorption of sodium and chloride, leading to diuresis.

Step-by-step explanation:

A patient with chronic kidney failure who is taking a loop diuretic should be advised to take the drug in the morning. Loop diuretics, such as furosemide, are medications that act on the kidneys to increase urine output. They inhibit the reabsorption of sodium (Na+) and chloride (Cl-) ions in the ascending limb of the loop of Henle, which leads to an increase in urine production (diuresis). Since these drugs can increase urination, taking them in the morning helps to avoid disrupting sleep with frequent trips to the restroom at night.