Question

A student is discussing lipid transport through the blood with a nursing instructor. The student asks the educator which apoproteins are important to lipid transport. Which responses by the educator are appropriate? Select all that apply.

1. A-I
2. A-II
3. A-III
4. A-IV
5. B-100

Answer 1

The appropriate apoproteins important to lipid transport are A-I, A-II, and B-100.

Step-by-step explanation:

Lipid transport in the blood involves various apoproteins associated with lipoproteins. Apoproteins play a crucial role in the structure and function of lipoproteins, facilitating their transport and metabolism. Apoprotein A-I (A-I) is a major component of high-density lipoprotein (HDL), promoting reverse cholesterol transport. A-II (A-II) is another apoprotein found in HDL, contributing to its stability. These HDL particles are responsible for transporting cholesterol away from peripheral tissues to the liver for excretion.

On the other hand, apoprotein B-100 (B-100) is associated with very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL). B-100 serves as a ligand for LDL receptor-mediated uptake, allowing cells to obtain cholesterol. However, apoproteins A-III (A-III) and A-IV (A-IV) are not directly involved in lipid transport; A-III has a regulatory role, and A-IV is associated with chylomicrons.

In summary, the appropriate apoproteins for lipid transport are A-I, A-II, and B-100. A-I and A-II are associated with HDL, contributing to reverse cholesterol transport, while B-100 is linked to VLDL and LDL, facilitating cholesterol delivery to cells. Understanding the roles of these apoproteins is crucial in comprehending the complex process of lipid metabolism and transport in the bloodstream.